The End of Alzheimer's:

The First Program to Prevent and Reverse Cognitive Decline

The instant New York Times and Wall Street Journal bestseller.

A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline.

Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease.

The End of Alzheimer’s

In this paradigm-shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline.  Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.

The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

Reviews for The End of Alzheimer’s

"Dr. Bredesen has provided enormous hope for the heretofore intractable clinical problem of Alzheimer’s. Bredesen’s early studies suggest that this approach can help and in many cases reverse early Alzheimer’s."

— Leroy Hood, MD, PhD
Awarded the National Medal of Science,
presented by President Barack Obama in 2011,
and founder of Institute for Systems Biology

"Dr. Dale Bredesen is a world-class neuroscientist-neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimer’s disease that will revolutionize the way we think about the disease."

— Dr. Jeffrey Bland
Founder of the Institute for Functional Medicine,
the Cleveland Clinic

"The End of Alzheimer’s” is a masterful, authoritative, and ultimately hopeful patient guide that will help you prevent and reverse Alzheimer’s disease, whether you have the ApoE4 gene or not. My patients fear Alzheimer’s more than any other diagnosis. This is the book to transmute fear into action."

— Sara Gottfried, MD
Author of the New York Times Bestseller “Younger"

"The End of Alzheimer’s is a monumental work. Dr. Bredesen completely recontextualizes this devastating condition away from a mysterious and unsolvable process to one that is both preventable and, yes, reversible."

— David Perlmutter, MD
Author of the #1 New York Times Bestsellers
“Grain Brain” & “Brain Maker"